Understanding how calcium channel problems contribute to neurodevelopmental disorders like autism
Dissecting the Role of Ca2+ Channel Dysfunction in the Pathogenesis of Neurodevelopmental Disorders
This study is looking at how problems with calcium channels in the brain might play a role in autism spectrum disorder (ASD), and it hopes to find ways to help people with ASD by understanding their unique genetic traits better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Maryland Baltimore NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11129221 on NIH RePORTER |
What this research studies
This research investigates the role of calcium channels in neurodevelopmental disorders, particularly autism spectrum disorder (ASD). It aims to identify how dysfunction in these channels affects brain signaling and contributes to the development of ASD. By studying genetic variants linked to calcium channel function, the research seeks to uncover the mechanisms that lead to these disorders. Patients may benefit from insights that could lead to targeted therapies or interventions based on their specific genetic profiles.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with autism spectrum disorder or those with a family history of neurodevelopmental disorders.
Not a fit: Patients with neurodevelopmental disorders not linked to calcium channel dysfunction may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for neurodevelopmental disorders, improving outcomes for affected individuals.
How similar studies have performed: Previous research has shown promising results in understanding the role of calcium signaling in neurodevelopmental disorders, suggesting that this approach could yield valuable insights.
Where this research is happening
Baltimore, United States
- University of Maryland Baltimore — Baltimore, United States (Active)
Researchers
- Principal investigator: Dick, Ivy E — University of Maryland Baltimore
- Study coordinator: Dick, Ivy E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.