Understanding how C. difficile affects patients
Official title: Redefining C.difficile patient outcomes through network medicine
Funded at Beth Israel Deaconess Medical Center · NIH-10933476 · Data updated 2026-11-12
This study is looking at how C. difficile affects people in different ways, from mild to serious symptoms, and aims to find helpful clues in their immune and gut health that could lead to better treatments and outcomes for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Beth Israel Deaconess Medical Center NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | September 22, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $191,484 |
| NIH project number | 5K23AI177749-02 |
| Project ID | NIH-10933476 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with C. difficile infections or those who are asymptomatic carriers.
✕Less likely to help
Patients with unrelated gastrointestinal conditions or those who have not been diagnosed with C. difficile may not benefit from this research.
What this research studies
This research investigates the various ways C. difficile can impact patients, ranging from mild symptoms to severe complications. By analyzing immune, microbial, and metabolic data from patients, the study aims to identify biological markers that can help improve patient outcomes. The goal is to redefine how we categorize C. difficile infections and enhance patient-centered outcomes through better understanding and treatment strategies.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies and better outcomes for patients suffering from C. difficile infections.
How similar studies have gone: Previous research has shown promise in using integrated data analysis to improve patient outcomes in infectious diseases, suggesting a potential for success in this novel approach.
Where this research is happening
-
Beth Israel Deaconess Medical Center
Boston, United States Active
Researchers
- Principal investigator: Villafuerte Galvez, Javier Andres — Beth Israel Deaconess Medical Center
- Study coordinator: Villafuerte Galvez, Javier Andres
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.