Understanding how Bunyaviruses change and spread through genetic exchange
Official title: US-UK Collab: Modelling reassortment at the cellular, clinical, and phylogenetic level in emerging Bunyaviruses
Funded at Triad National Security, LLC · NIH-10877933 · Data updated 2026-11-12
This study looks at how certain viruses, called Bunyaviruses, share their genes when they infect the same cell, which could help us understand how they evolve and spread, ultimately leading to better ways to prevent and treat infections for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Triad National Security, LLC NIH-funded |
| Lab location | 1 site (Los Alamos, UNITED STATES) |
| Project start | July 1, 2021 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $447,570 |
| NIH project number | 5R01AI167048-04 |
| Project ID | NIH-10877933 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research are individuals at risk for infections caused by Bunyaviruses, such as those living in endemic areas.
✕Less likely to help
Patients who are not at risk for Bunyavirus infections or those with unrelated health conditions may not receive any benefit from this research.
What this research studies
This research investigates how Bunyaviruses, a family of viruses that can cause severe diseases, exchange genetic material when they infect the same cell. By developing mathematical models, the research aims to quantify the life cycle of these viruses and understand how their genetic reassortment affects their evolution and ability to spread. This could provide insights into the dynamics of viral infections and help in developing strategies for prevention and control. Patients may benefit from improved understanding of these viruses and potential advancements in treatment options.
Why it matters
Potential benefit: If successful, this research could lead to better prevention and treatment strategies for diseases caused by Bunyaviruses.
How similar studies have gone: Previous research on viral reassortment, particularly with influenza viruses, has shown significant success in understanding viral evolution and public health implications.
Where this research is happening
-
Triad National Security, LLC
Los Alamos, United States Active
Researchers
- Principal investigator: Molina-Paris, Carmen — Triad National Security, LLC
- Study coordinator: Molina-Paris, Carmen
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.