Understanding how brown fat helps burn calories and affects metabolism
Quantitative and functional analysis of brown fat nutrient fluxes in vivo and its role in organ metabolite exchange
This study is looking at how brown fat helps burn calories and improve health, which could lead to new ways to help people with obesity and type 2 diabetes feel better and manage their weight.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of Massachusetts Med Sch Worcester NIH-funded |
| Lab location | 1 site (Worcester, United States) |
| Project ID | NIH-11099708 on NIH RePORTER |
What this research studies
This research investigates the role of brown adipose tissue (BAT) in calorie burning and its impact on metabolic health. By analyzing how BAT metabolizes nutrients and interacts with other organs, the study aims to uncover new therapeutic strategies for conditions like obesity and type 2 diabetes. Patients may benefit from insights into how stimulating brown fat could enhance energy expenditure and improve metabolic outcomes. The research employs advanced metabolic analysis techniques to evaluate the function of brown fat in living organisms.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old who are dealing with obesity or related metabolic conditions.
Not a fit: Patients who are under 21 years old or do not have issues related to obesity or metabolic syndrome may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that help patients manage weight and reduce the risk of metabolic diseases.
How similar studies have performed: Previous research has shown promising results in stimulating brown fat for metabolic benefits, indicating that this approach has potential for success.
Where this research is happening
Worcester, United States
- Univ of Massachusetts Med Sch Worcester — Worcester, United States (Active)
Researchers
- Principal investigator: Guertin, David a — Univ of Massachusetts Med Sch Worcester
- Study coordinator: Guertin, David a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.