Understanding how breathing control improves after short periods of low oxygen.
Regulation of Intermittent Hypoxia-Induced Respiratory Motor Plasticity
This study is looking at how the brain helps us breathe better when there's not enough oxygen, and it's aimed at finding new ways to help people with spinal injuries or muscle diseases breathe more easily.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project ID | NIH-10458511 on NIH RePORTER |
What this research studies
This research investigates how the nervous system adapts to low oxygen levels, specifically focusing on the mechanisms that enhance breathing control. It examines two pathways in the brain that influence respiratory motor function after experiencing intermittent hypoxia. By understanding these pathways, the research aims to develop treatments that could improve breathing in individuals with spinal injuries or neuromuscular diseases. The study involves both laboratory experiments and potential clinical applications to enhance respiratory function.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with cervical spinal injuries or neuromuscular diseases that affect their breathing.
Not a fit: Patients with respiratory conditions unrelated to spinal injuries or neuromuscular diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that significantly improve breathing for patients with respiratory challenges.
How similar studies have performed: Previous research has shown promising results in understanding respiratory motor plasticity, making this approach a continuation of established findings.
Where this research is happening
Gainesville, United States
- University of Florida — Gainesville, United States (Active)
Researchers
- Principal investigator: Mitchell, Gordon S. — University of Florida
- Study coordinator: Mitchell, Gordon S.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.