Understanding how breast cancer spreads and resists treatment
Evolutionary dynamics and microenvironmental determinants of metastatic breast cancer
['FUNDING_OTHER'] · STANFORD UNIVERSITY · NIH-10977547
This study is looking at how breast cancer spreads and why some treatments don't work, using special lab models and samples from patients to find new ways to improve care for those with breast cancer.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | STANFORD UNIVERSITY (nih funded) |
| Locations | 1 site (STANFORD, UNITED STATES) |
| Trial ID | NIH-10977547 on ClinicalTrials.gov |
What this research studies
This research investigates the factors that contribute to the spread of breast cancer and its resistance to therapies. It focuses on understanding the timing of when cancer cells metastasize and how interactions between cancer cells and their surrounding environment influence this process. The study utilizes advanced computational models and a unique collection of patient-derived organoids to explore the complexities of breast cancer behavior and treatment responses. By analyzing these models and patient samples, the research aims to uncover new insights that could lead to improved treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with metastatic breast cancer who are undergoing treatment.
Not a fit: Patients with early-stage breast cancer or those who do not have a diagnosis of breast cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for metastatic breast cancer, potentially improving survival rates and quality of life for patients.
How similar studies have performed: Previous research has shown promise in understanding cancer metastasis and treatment resistance using similar approaches, indicating a potential for success in this area.
Where this research is happening
STANFORD, UNITED STATES
- STANFORD UNIVERSITY — STANFORD, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CURTIS, CHRISTINA N — STANFORD UNIVERSITY
- Study coordinator: CURTIS, CHRISTINA N
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Breast Cancer, Breast Cancer Model, Breast Cancer Patient