Understanding how breast cancer spreads
PI3K Beta regulation of tumor metastasis
This project aims to understand how breast cancer spreads throughout the body, hoping to find new ways to stop it.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Albert Einstein College of Medicine NIH-funded |
| Lab location | 1 site (Bronx, United States) |
| Project ID | NIH-11126042 on NIH RePORTER |
What this research studies
Breast cancer can become very serious when it spreads to other parts of the body, a process called metastasis. We know that certain cells, like immune cells called macrophages and blood cells called platelets, play a big role in helping cancer cells move and grow in new locations. This project focuses on a specific protein, PI3K Beta, which appears to be a key player in this spreading process. By learning more about how PI3K Beta works, we hope to develop new treatments that can prevent breast cancer from spreading.
Who could benefit from this research
Good fit: This foundational research is for future patients with breast cancer, particularly those at risk of or experiencing metastasis.
Not a fit: Patients would not receive direct benefit from this basic science project, as it is focused on understanding disease mechanisms rather than immediate treatment.
Why it matters
Potential benefit: If successful, this work could lead to new medications that specifically target PI3K Beta to prevent or slow down breast cancer metastasis.
How similar studies have performed: While inhibitors for PI3K Beta exist and have been explored for tumor growth, this project is novel in directly focusing on its role in preventing metastasis.
Where this research is happening
Bronx, United States
- Albert Einstein College of Medicine — Bronx, United States (Active)
Researchers
- Principal investigator: Bresnick, Anne R — Albert Einstein College of Medicine
- Study coordinator: Bresnick, Anne R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.