Understanding how brainstem neurons control reproductive hormone secretion
Official title: Investigation of brainstem neurons in the regulation of gonadotropin secretion
Funded at Colorado State University · NIH-11009062 · Data updated 2026-11-12
This study is looking at how certain brain cells control the release of important hormones for fertility, specifically focusing on how they affect luteinizing hormone (LH), and it aims to help us understand more about reproductive health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Colorado State University NIH-funded |
| Lab location | 1 site (Fort Collins, United States) |
| Project start | January 25, 2023 |
| Project end | November 30, 2025 |
| Funding year | 2025 |
| Award (this year) | $249,000 |
| NIH project number | 5R00HD104994-05 |
| Project ID | NIH-11009062 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals experiencing reproductive health issues, such as amenorrhea or infertility.
✕Less likely to help
Patients with reproductive health issues unrelated to hormonal regulation may not benefit from this research.
What this research studies
This research investigates the neural pathways that regulate the secretion of gonadotropins, which are hormones crucial for reproductive function. By focusing on specific neurons in the brainstem and hypothalamus, the study aims to uncover how these neurons influence the release of luteinizing hormone (LH), a key hormone in fertility. The research employs advanced techniques to map the interactions between different neuron populations and their effects on hormone levels, which could lead to new insights into reproductive health.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for reproductive disorders and enhance our understanding of fertility regulation.
How similar studies have gone: Previous research has shown promising results in understanding hormonal regulation through neural pathways, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Colorado State University
Fort Collins, United States Active
Researchers
- Principal investigator: Mccosh, Richard Bryan — Colorado State University
- Study coordinator: Mccosh, Richard Bryan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.