Understanding how brain tumor cells differ from normal brain cells
Decoding the molecular basis of cellular identity in adult malignant gliomas
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · NIH-10738302
This study is looking at the differences between brain tumor cells and healthy brain cells to find new ways to treat gliomas, which could help patients get better treatment options in the future.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO (nih funded) |
| Locations | 1 site (SAN FRANCISCO, UNITED STATES) |
| Trial ID | NIH-10738302 on ClinicalTrials.gov |
What this research studies
This research investigates the molecular differences between malignant glioma cells and normal brain cells to identify new treatment strategies for brain tumors. By analyzing over 4,000 tissue samples, the study aims to uncover the unique gene expression patterns that characterize these cancerous cells. This approach could lead to a better understanding of how gliomas develop and progress, potentially guiding the development of targeted therapies. Patients may benefit from insights that could inform more effective treatment options in the future.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults diagnosed with malignant gliomas, such as astrocytomas or glioblastomas.
Not a fit: Patients with non-malignant brain tumors or those without brain tumors may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of more effective treatments for malignant gliomas.
How similar studies have performed: Previous research has shown promise in understanding cancer cell biology through gene expression analysis, indicating that this approach could yield valuable insights.
Where this research is happening
SAN FRANCISCO, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN FRANCISCO — SAN FRANCISCO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: OLDHAM, MICHAEL CLARK — UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
- Study coordinator: OLDHAM, MICHAEL CLARK
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.