Understanding how brain swelling affects nerve cell activity after brain injury

Who could benefit from this research

What this research studies

This research investigates the mechanisms behind cerebral edema, which is swelling in the brain that can occur after a traumatic brain injury (TBI). The team will explore how this swelling impacts the excitability of neurons and brain networks, particularly focusing on changes in a specific transporter that regulates chloride levels in nerve cells. By using advanced imaging techniques, they aim to uncover the relationship between neuronal swelling and changes in brain activity, which could lead to new treatment strategies for TBI. The study will analyze both mild and severe injuries to provide a comprehensive understanding of the condition.

Why it matters

Where this research is happening

• Texas A&m University Health Science Ctr
  College Station, United States Active

Researchers

• Principal investigator: Pokam, Punam Adhik — Texas A&m University Health Science Ctr
• Study coordinator: Pokam, Punam Adhik

Related research

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.