Understanding how brain stimulation can improve treatment for Parkinson's disease
Characterizing Evoked Potentials of Deep Brain Stimulation for Parkinson's Disease
['FUNDING_FELLOWSHIP'] · DUKE UNIVERSITY · NIH-11009058
This study is looking at how to make deep brain stimulation surgery for Parkinson's disease better by using special signals to help doctors place the stimulation leads more accurately, which could lead to quicker and more effective treatments for patients.
Quick facts
| Phase | ['FUNDING_FELLOWSHIP'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | DUKE UNIVERSITY (nih funded) |
| Locations | 1 site (DURHAM, UNITED STATES) |
| Trial ID | NIH-11009058 on ClinicalTrials.gov |
What this research studies
This research investigates deep brain stimulation (DBS) as a surgical treatment for Parkinson's disease, focusing on improving the placement of DBS leads to enhance patient outcomes. The study aims to use evoked potentials (EPs) as biomarkers to guide the precise placement of these leads, potentially allowing for faster and more accurate procedures. By examining how stimulation amplitude, lead location, and anesthesia affect EPs, the research seeks to correlate these factors with symptom relief. This could lead to a more efficient DBS process, possibly even allowing for procedures to be performed under anesthesia.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with Parkinson's disease who are considering deep brain stimulation as a treatment option.
Not a fit: Patients who are not candidates for deep brain stimulation or those with advanced Parkinson's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved surgical outcomes and reduced symptoms for patients with Parkinson's disease.
How similar studies have performed: Previous research has shown promise in using biomarkers for improving surgical outcomes in various neurological procedures, suggesting potential success for this approach.
Where this research is happening
DURHAM, UNITED STATES
- DUKE UNIVERSITY — DURHAM, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DALE, JAHRANE ANTONIO — DUKE UNIVERSITY
- Study coordinator: DALE, JAHRANE ANTONIO
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.