Understanding how brain stimulation can improve cognitive training in older adults
Mechanisms, response heterogeneity and dosing from MRI-derived electric field models in tDCS augmented cognitive training: a secondary data analysis of the ACT study
This study is looking at how a special brain stimulation technique, combined with mental exercises, can help older adults who are at risk for Alzheimer's disease, and it aims to find out how different brain structures and levels of stimulation can make the treatment work better for each person.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project ID | NIH-10892337 on NIH RePORTER |
What this research studies
This research investigates the effects of transcranial direct current stimulation (tDCS) combined with cognitive training on cognitive decline in older adults, particularly those at risk for Alzheimer's disease. By analyzing data from a previous trial, the study aims to uncover how individual differences in brain structure and the amount of electrical current used can influence treatment outcomes. The goal is to refine the tDCS approach to better target and personalize treatment for each patient, potentially leading to more effective interventions for cognitive decline.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults experiencing cognitive decline or at risk for Alzheimer's disease.
Not a fit: Patients who are not experiencing cognitive decline or who do not have risk factors for Alzheimer's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective cognitive training interventions that help slow or prevent the progression of Alzheimer's disease in older adults.
How similar studies have performed: Previous studies have shown promise in using tDCS for cognitive enhancement, but this research aims to refine and personalize the approach, making it a novel exploration.
Where this research is happening
Gainesville, United States
- University of Florida — Gainesville, United States (Active)
Researchers
- Principal investigator: Fang, Ruogu — University of Florida
- Study coordinator: Fang, Ruogu
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.