Understanding how brain signals support working memory
Chronic and acute molecular programs enabling working memory
['FUNDING_R01'] · ROCKEFELLER UNIVERSITY · NIH-11142575
This study is looking at how certain parts of the brain help us remember things for a short time, like when we're reading or driving, and it hopes to find new ways to help people with memory problems, especially those with ADHD or schizophrenia.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ROCKEFELLER UNIVERSITY (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-11142575 on ClinicalTrials.gov |
What this research studies
This research investigates the molecular mechanisms in the brain that enable working memory, which is crucial for everyday tasks like reading and driving. It focuses on the role of the thalamus and prefrontal cortex in maintaining short-term memory and aims to identify new therapeutic targets for improving memory deficits. By studying both chronic and acute molecular programs, the research seeks to uncover how specific receptors in the thalamus influence memory function. Patients may benefit from insights that could lead to new treatments for conditions like ADHD and schizophrenia.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with ADHD, learning disabilities, or schizophrenia who experience working memory challenges.
Not a fit: Patients without cognitive deficits or those not affected by working memory issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve working memory in individuals with cognitive deficits.
How similar studies have performed: Previous research has shown promise in understanding the brain mechanisms underlying memory, but this specific approach is novel and untested.
Where this research is happening
NEW YORK, UNITED STATES
- ROCKEFELLER UNIVERSITY — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: RAJASETHUPATHY, PRIYA — ROCKEFELLER UNIVERSITY
- Study coordinator: RAJASETHUPATHY, PRIYA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Attention deficit hyperactivity disorder