Understanding how brain signals influence behavior and mental health
Official title: Bridging Scales to Understand Endogenous Neuromodulation and its Regulation
Funded at Duke University · NIH-11051258 · Data updated 2026-11-12
This study is looking at how certain parts of the brain can help us understand and improve our behavior and mental health, and if you join, you might learn ways to better manage your mental health through brain training.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project start | March 8, 2023 |
| Project end | February 28, 2027 |
| Funding year | 2025 |
| Award (this year) | $488,365 |
| NIH project number | 5R01MH131667-03 |
| Project ID | NIH-11051258 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals experiencing mental health challenges or those interested in cognitive enhancement.
✕Less likely to help
Patients with neurological conditions unrelated to neuromodulation or those not experiencing mental health issues may not benefit from this research.
What this research studies
This research investigates how specific brain regions, known as neuromodulatory nuclei, detect and influence brain activity patterns that affect behavior. By using advanced neuroimaging and behavioral techniques, the team aims to understand how these nuclei can be regulated to improve mental health outcomes. Participants may engage in training to help self-regulate brain activity, which could lead to insights on how to better manage mental disorders. The study employs innovative methods to analyze brain function in real-time, potentially linking brain activity to cognitive processes.
Why it matters
Potential benefit: If successful, this research could lead to new interventions for mental health disorders by enhancing our understanding of brain function and behavior.
How similar studies have gone: Previous research has shown promise in using neurofeedback and neuromodulation techniques to improve mental health outcomes, suggesting that this approach could be effective.
Where this research is happening
-
Duke University
Durham, United States Active
Researchers
- Principal investigator: Adcock, Rachel Alison — Duke University
- Study coordinator: Adcock, Rachel Alison
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.