Understanding how brain signals affect motivation and reward-seeking behavior
Neural signals controlling generalized deficits in motivation
This study looks at how the brain controls motivation and the desire for rewards, especially in animals, to help us understand why some people with mental health issues struggle with motivation.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas San Antonio NIH-funded |
| Lab location | 1 site (San Antonio, United States) |
| Project ID | NIH-10986123 on NIH RePORTER |
What this research studies
This research investigates the neural signals that control motivation and reward-seeking behaviors, which are often impaired in mental health disorders. Using a novel rodent task, the study examines how animals respond to different reward options and how their motivation changes when the size of these rewards is altered. By categorizing the animals based on their reward-seeking strategies, researchers aim to uncover the underlying neural mechanisms that contribute to motivation deficits. This approach could lead to a better understanding of how these behaviors are regulated in the brain.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing motivation deficits associated with mental health conditions.
Not a fit: Patients who do not have motivation-related issues or those with conditions unrelated to the neural mechanisms being studied may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide insights into the biological basis of motivation deficits, potentially leading to new treatments for mental health disorders.
How similar studies have performed: While this approach is innovative, similar studies have shown promise in understanding motivation and reward-seeking behaviors in animal models.
Where this research is happening
San Antonio, United States
- University of Texas San Antonio — San Antonio, United States (Active)
Researchers
- Principal investigator: Wanat, Matthew J. — University of Texas San Antonio
- Study coordinator: Wanat, Matthew J.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.