Understanding how brain signals affect addiction and decision-making

Imaging neuromodulation in the brain

NIH-funded research California Institute of Technology · NIH-11021060

This study is looking at how certain brain cells in fruit flies affect feelings and behaviors related to addiction, which could help us understand more about how addiction works in people.

Quick facts

Grant typeR37 grant
Study typeNIH-funded research
Funding institutionCalifornia Institute of Technology NIH-funded
Lab location1 site (Pasadena, United States)
Project IDNIH-11021060 on NIH RePORTER

What this research studies

This research investigates the brain mechanisms that influence motivation, arousal, and emotions related to addiction. By using the fruit fly Drosophila as a model organism, the study explores how specific neurons control persistent internal states that affect behavior and decision-making. The researchers aim to uncover the role of certain brain cells in promoting social arousal and how these processes relate to addiction. This work could lead to insights into the neurobiological underpinnings of addiction and its effects on behavior.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults over 21 years old who are struggling with addiction or addictive disorders.

Not a fit: Patients who are under 21 years old or do not have issues related to addiction may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide new insights into the treatment of addiction by identifying how brain signals influence behavior.

How similar studies have performed: Previous research using similar approaches in animal models has shown promising results in understanding addiction mechanisms.

Where this research is happening

Pasadena, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions addictive disorder
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.