Understanding how brain serotonin affects eating and weight management
5-HT NEURONS AND MEAL REGULATION
This study is looking at how certain brain cells that use serotonin help control eating and weight, and it hopes to find new ways to treat obesity by understanding how these cells work with other brain signals.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10869901 on NIH RePORTER |
What this research studies
This research investigates the role of serotonin neurons in regulating food intake and body weight. It aims to uncover how these neurons interact with other brain signals, particularly GABA and dopamine, to influence eating behaviors. By studying mice with specific genetic modifications, the research seeks to identify mechanisms that could lead to new treatments for obesity. The findings may help develop safer and more effective weight loss therapies by targeting serotonin pathways.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals struggling with obesity or weight management issues.
Not a fit: Patients who are not overweight or do not have issues related to body weight regulation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new, safer treatments for obesity that effectively regulate appetite and body weight.
How similar studies have performed: Previous research has shown promise in targeting serotonin pathways for weight management, but this specific approach is still being explored.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: Mcdermott, Kristine Marie — Baylor College of Medicine
- Study coordinator: Mcdermott, Kristine Marie
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.