Understanding how brain regions influence decision-making and compulsive behaviors
Official title: Frontostriatal Dynamics During Decision-Making
Funded at University of California Berkeley · NIH-11046820 · Data updated 2026-11-12
This study looks at how different parts of the brain work together to influence decision-making and control compulsive behaviors, like those seen in addiction and eating disorders, with the hope of finding new ways to help people manage these challenges.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Berkeley NIH-funded |
| Lab location | 1 site (Berkeley, United States) |
| Project start | September 21, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $678,430 |
| NIH project number | 1R01MH132640-01A1 |
| Project ID | NIH-11046820 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with neuropsychiatric disorders characterized by compulsive behaviors, such as obsessive-compulsive disorder, addiction, or eating disorders.
✕Less likely to help
Patients without neuropsychiatric disorders or those whose compulsive behaviors are not linked to decision-making processes may not benefit from this research.
What this research studies
This research investigates the brain's decision-making processes, particularly focusing on how certain areas of the brain, like the orbitofrontal cortex and caudate nucleus, interact to control compulsive behaviors seen in disorders such as addiction and eating disorders. By examining the dynamics between these brain regions, the research aims to uncover how automatic and goal-directed decision-making processes are managed. Patients may benefit from insights that could lead to new treatment strategies for managing compulsive behaviors and improving decision-making in neuropsychiatric disorders.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for individuals struggling with compulsive behaviors and decision-making disorders.
How similar studies have gone: Previous research has shown promising results in understanding the brain's decision-making processes, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of California Berkeley
Berkeley, United States Active
Researchers
- Principal investigator: Wallis, Joni D — University of California Berkeley
- Study coordinator: Wallis, Joni D
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.