Understanding how brain regions coordinate for memory and learning.
Official title: Mechanisms and functions of temporal coordination in the entorhinal-hippocampal network
Funded at Cornell University · NIH-11049736 · Data updated 2026-11-12
This study looks at how certain parts of the brain work together to help us learn and remember things, using rats to explore the timing of brain activity, and the findings could help us understand memory problems in people.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cornell University NIH-funded |
| Lab location | 1 site (Ithaca, United States) |
| Project start | September 23, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $571,694 |
| NIH project number | 1R01MH136355-01A1 |
| Project ID | NIH-11049736 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals experiencing cognitive decline or memory-related disorders.
✕Less likely to help
Patients with no cognitive impairments or those not experiencing memory issues may not benefit from this research.
What this research studies
This research investigates the mechanisms behind how specific brain regions, particularly the entorhinal and hippocampal areas, work together to support learning and memory. By examining the timing of neuronal activity and using advanced techniques like optogenetics and multi-region recordings, the study aims to uncover how different types of memory are formed and recalled. The research focuses on oscillatory patterns in brain activity that are believed to play a crucial role in these cognitive processes, particularly in rats. Insights gained from this research could help in understanding cognitive impairments in humans.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for enhancing memory and learning, potentially benefiting individuals with cognitive impairments.
How similar studies have gone: Previous research has shown promising results in understanding brain oscillations and their role in memory, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Cornell University
Ithaca, United States Active
Researchers
- Principal investigator: Fernandez-Ruiz, Antonio — Cornell University
- Study coordinator: Fernandez-Ruiz, Antonio
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.