Understanding how brain regions coordinate for memory and learning.
Mechanisms and functions of temporal coordination in the entorhinal-hippocampal network
This study looks at how certain parts of the brain work together to help us learn and remember things, using rats to explore the timing of brain activity, and the findings could help us understand memory problems in people.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cornell University NIH-funded |
| Lab location | 1 site (Ithaca, United States) |
| Project ID | NIH-11049736 on NIH RePORTER |
What this research studies
This research investigates the mechanisms behind how specific brain regions, particularly the entorhinal and hippocampal areas, work together to support learning and memory. By examining the timing of neuronal activity and using advanced techniques like optogenetics and multi-region recordings, the study aims to uncover how different types of memory are formed and recalled. The research focuses on oscillatory patterns in brain activity that are believed to play a crucial role in these cognitive processes, particularly in rats. Insights gained from this research could help in understanding cognitive impairments in humans.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing cognitive decline or memory-related disorders.
Not a fit: Patients with no cognitive impairments or those not experiencing memory issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for enhancing memory and learning, potentially benefiting individuals with cognitive impairments.
How similar studies have performed: Previous research has shown promising results in understanding brain oscillations and their role in memory, suggesting that this approach could yield valuable insights.
Where this research is happening
Ithaca, United States
- Cornell University — Ithaca, United States (Active)
Researchers
- Principal investigator: Fernandez-Ruiz, Antonio — Cornell University
- Study coordinator: Fernandez-Ruiz, Antonio
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.