Understanding how brain proteins affect memory formation
Activity-Dependent Regulation of CaMKII and Synaptic Plasticity
['FUNDING_R37'] · BRANDEIS UNIVERSITY · NIH-11113840
This study is looking at how a protein called CaMKII helps us form memories, and it's for anyone interested in understanding how our brains work and what might affect our ability to remember things.
Quick facts
| Phase | ['FUNDING_R37'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BRANDEIS UNIVERSITY (nih funded) |
| Locations | 1 site (WALTHAM, UNITED STATES) |
| Trial ID | NIH-11113840 on ClinicalTrials.gov |
What this research studies
This research investigates the role of a specific protein, CaMKII, in the formation of memories by examining how it is produced and localized in the brain. The study will explore whether certain sequences in the protein's genetic material are necessary for its function and how disruptions in this process might impact memory. By using advanced techniques like real-time assays and genome editing, researchers aim to uncover the mechanisms behind memory formation and the potential factors that influence it.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals aged 21 and older who may be experiencing memory-related issues or are interested in the biological mechanisms of memory.
Not a fit: Patients with no interest in memory research or those under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights into memory-related disorders and potential therapeutic strategies for improving memory function.
How similar studies have performed: Previous research has shown promising results in understanding the role of CaMKII in memory, indicating that this approach has potential for significant findings.
Where this research is happening
WALTHAM, UNITED STATES
- BRANDEIS UNIVERSITY — WALTHAM, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GRIFFITH, LESLIE C — BRANDEIS UNIVERSITY
- Study coordinator: GRIFFITH, LESLIE C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.