Understanding how brain processes affect sentence production in people with aphasia after a stroke
Official title: Neurocognitive Mechanisms of Sentence Production Impairment in Aphasia
Funded at Univ of Maryland, College Park · NIH-10885166 · Data updated 2026-11-12
This study is looking at how brain processes affect the ability to form sentences in people who have trouble speaking after a stroke, with the goal of finding better ways to help them communicate.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of Maryland, College Park NIH-funded |
| Lab location | 1 site (College Park, United States) |
| Project start | July 15, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $616,172 |
| NIH project number | 5R01DC020483-02 |
| Project ID | NIH-10885166 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have experienced a stroke and are diagnosed with post-stroke agrammatic aphasia.
✕Less likely to help
Patients who do not have aphasia or have other forms of communication disorders unrelated to agrammatic aphasia may not benefit from this research.
What this research studies
This research investigates the complex mechanisms behind sentence production impairments in individuals with post-stroke agrammatic aphasia (PSA-G). It aims to improve communication interventions by exploring how various cognitive and motor processes interact during sentence formation and how these processes are disrupted in PSA-G. The study will utilize advanced methodologies to analyze the neural dynamics involved in language production, focusing on the timing and coordination of brain activity. By identifying the specific neural alterations that contribute to communication difficulties, the research seeks to inform more effective therapeutic strategies for patients.
Why it matters
Potential benefit: If successful, this research could lead to improved communication therapies for individuals suffering from aphasia, enhancing their ability to express themselves.
How similar studies have gone: While some research has explored aspects of aphasia treatment, this study's specific focus on the neural mechanisms of sentence production in PSA-G represents a novel approach.
Where this research is happening
-
Univ of Maryland, College Park
College Park, United States Active
Researchers
- Principal investigator: Faroqi Shah, Yasmeen — Univ of Maryland, College Park
- Study coordinator: Faroqi Shah, Yasmeen
Related research
Other NIH-funded projects on the same topics.
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Communication Bridge: Improving language therapy for people with primary progressive aphasia
A proven language-therapy program called Communication Bridge helps people with primary progressive aphasia improve and maintain how they communicate with others.
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Neural signals linked to recovery from aphasia after stroke
This grant follows people who recently had a stroke and aphasia to understand why some recover language abilities better than others.
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Bilingualism and language resilience in Hispanic people with primary progressive aphasia
Researchers compare different bilingual experiences to see how they relate to language decline and thinking skills in Hispanic adults with primary progressive aphasia.
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Functional reorganization of language and general brain networks in aphasia
This project studies how language areas and general brain networks work together to help people recover language after a stroke, by looking at brain activity and responses to language tasks.
-
eSANA: revealing and improving AAC use after stroke for aphasia
A project to explore how people with aphasia after a stroke can best use augmentative and alternative communication (AAC) during early rehabilitation.
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Cortical Organization of Syntax in Aphasia
A patient-facing study to understand how brain injury affects sentence structure and help people with aphasia communicate more clearly.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.