Understanding how brain networks process sensory information

CRCNS: Dynamics of thalamocortical networks during sensory discrimination

NIH-funded research Michigan State University · NIH-10867483

This study is looking at how different parts of the brain work together to help us process what we see and hear, and it's for anyone interested in understanding how our brains handle attention and memory, especially in people with brain disorders.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMichigan State University NIH-funded
Lab location1 site (East Lansing, United States)
Project IDNIH-10867483 on NIH RePORTER

What this research studies

This research investigates the interactions within thalamocortical networks, which are essential for sensory processing and cognitive functions like attention and memory. By measuring brain activity during sensory discrimination tasks, the study aims to clarify how different parts of the thalamus and cortex communicate. The researchers will use advanced techniques, including optogenetic inhibition, to simulate impairments and understand the roles of specific thalamic regions. This work could provide insights into the neural mechanisms underlying cognitive functions and their dysfunction in various neurological disorders.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals experiencing cognitive impairments related to conditions such as Alzheimer's disease.

Not a fit: Patients with no cognitive impairments or those not affected by neurological disorders may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and treatment options for cognitive impairments associated with neurological disorders.

How similar studies have performed: Previous research has shown promising results in understanding thalamocortical dynamics, but this specific approach using optogenetic techniques is relatively novel.

Where this research is happening

East Lansing, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndromeAlzheimer's Disease
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.