Understanding how brain networks control speech production
Cortical-Basal Ganglia Speech Networks
This study is looking at how a part of the brain called the basal ganglia helps us talk by watching brain activity in real-time while patients speak during surgery, so we can better understand how our brains control speech.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10872252 on NIH RePORTER |
What this research studies
This research investigates the role of the basal ganglia in speech production by examining how neural activity in this brain region interacts with cortical processes. Using advanced techniques like electrocorticography during awake deep brain stimulation surgeries, researchers aim to capture real-time neural activity while patients speak. The study focuses on understanding how specific neural signals correlate with different aspects of speech, such as articulation and motor control. By analyzing this data, the research seeks to provide insights into the neural mechanisms underlying speech production.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients undergoing deep brain stimulation surgery for conditions that affect speech, such as dystonia.
Not a fit: Patients who do not have speech production issues or are not candidates for deep brain stimulation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for speech disorders and better understanding of speech production mechanisms.
How similar studies have performed: Other research has shown promise in understanding brain networks involved in speech, but this specific approach using direct neural recordings during speech production is relatively novel.
Where this research is happening
Boston, United States
- Massachusetts General Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Richardson, Robert Mark — Massachusetts General Hospital
- Study coordinator: Richardson, Robert Mark
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.