Understanding how brain metabolism affects cognitive functions and diseases.
Official title: Center of Biomedical Research Excellence in CNS Metabolism
Funded at University of Kentucky · NIH-11077851 · Data updated 2026-11-12
This study is looking at how the brain's energy use affects its ability to function properly, which is important for thinking and memory, and it's aimed at helping people with conditions like Alzheimer's and brain injuries by better understanding these connections.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Kentucky NIH-funded |
| Lab location | 1 site (Lexington, United States) |
| Project start | May 15, 2023 |
| Project end | February 29, 2028 |
| Funding year | 2025 |
| Award (this year) | $2,122,307 |
| NIH project number | 5P20GM148326-03 |
| Project ID | NIH-11077851 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with neurological conditions such as Alzheimer's disease, epilepsy, or those who have suffered brain injuries.
✕Less likely to help
Patients with conditions unrelated to CNS metabolism or those without neurological disorders may not benefit from this research.
What this research studies
This research investigates the relationship between central nervous system (CNS) metabolism and neuronal excitability, which are crucial for cognition, memory, and behavior. It aims to uncover the biochemical mechanisms linking CNS metabolism to various neurological disorders, including Alzheimer's disease and brain injuries. The University of Kentucky is establishing a multidisciplinary center that combines expertise in glucose biology, neuronal signaling, and advanced imaging techniques to explore these connections. By integrating diverse scientific approaches, the research seeks to enhance our understanding of how metabolic processes influence brain health and disease.
Why it matters
Potential benefit: If successful, this research could lead to new insights and therapeutic strategies for treating neurological disorders.
How similar studies have gone: Previous research has shown promising results in understanding CNS metabolism's role in neurological diseases, indicating that this approach has potential for significant breakthroughs.
Where this research is happening
-
University of Kentucky
Lexington, United States Active
Researchers
- Principal investigator: Sullivan, Patrick G — University of Kentucky
- Study coordinator: Sullivan, Patrick G
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.