Understanding how brain injuries affect sleep disorders in veterans
Neural mechanisms underlying the connection between Neurotrauma and REM Sleep Behavior Disorder
This study is looking at how brain injuries and PTSD might lead to sleep problems, specifically a condition called REM Sleep Behavior Disorder, in veterans, and it hopes to find out what causes these sleep issues and how they might relate to future health concerns.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Portland VA Medical Center NIH-funded |
| Lab location | 1 site (Portland, United States) |
| Project ID | NIH-11109418 on NIH RePORTER |
What this research studies
This research investigates the connection between neurotrauma, such as traumatic brain injury (TBI) and posttraumatic stress disorder (PTSD), and the development of REM Sleep Behavior Disorder (RBD) in veterans. It aims to explore how these conditions disrupt normal sleep patterns, particularly the muscle paralysis that typically occurs during REM sleep. By studying the neural mechanisms involved, the research seeks to identify predictors and pathways that link neurotrauma to sleep disturbances and potential future neurodegenerative diseases. Veterans with a history of TBI and PTSD will be the focus of this investigation.
Who could benefit from this research
Good fit: Ideal candidates for this research are veterans who have experienced traumatic brain injuries or PTSD.
Not a fit: Patients without a history of neurotrauma or sleep disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for sleep disorders in veterans, potentially reducing the risk of developing Parkinson's Disease.
How similar studies have performed: Previous studies have indicated a strong link between neurotrauma and sleep disorders, suggesting that this research builds on established findings rather than exploring an untested area.
Where this research is happening
Portland, United States
- Portland VA Medical Center — Portland, United States (Active)
Researchers
- Principal investigator: Lim, Miranda M — Portland VA Medical Center
- Study coordinator: Lim, Miranda M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.