Understanding how brain injuries affect memory in children
INJURY-INDUCED SPATIAL MEMORY IMPAIRMENTS ARE LINKED TO UNCOORDINATED HIPPOCAMPAL NEURONAL FIRING
This study is looking at how a traumatic brain injury affects memory in kids and young adults, especially how it makes it harder for them to remember where things are and navigate their surroundings, with the goal of finding ways to help improve their memory skills.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Hosp of Philadelphia NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11011479 on NIH RePORTER |
What this research studies
This research investigates the impact of traumatic brain injury (TBI) on memory functions in children and young adults. It focuses on how damage to the hippocampus, a critical brain area for learning and memory, leads to difficulties in spatial memory, which is essential for navigating and understanding our environment. The study employs advanced techniques to analyze neuronal firing patterns and rhythms in the hippocampus, aiming to uncover the underlying mechanisms of memory impairment following TBI. By understanding these processes, the research seeks to identify potential therapeutic targets for improving cognitive outcomes in affected individuals.
Who could benefit from this research
Good fit: Ideal candidates for this research are children and young adults aged 0-21 who have experienced a traumatic brain injury.
Not a fit: Patients who have not experienced a traumatic brain injury or those outside the age range of 0-21 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that enhance memory recovery for children and young adults who have suffered brain injuries.
How similar studies have performed: Previous research has shown promising results in understanding memory impairments related to brain injuries, suggesting that this approach could yield valuable insights.
Where this research is happening
Philadelphia, United States
- Children's Hosp of Philadelphia — Philadelphia, United States (Active)
Researchers
- Principal investigator: Cohen, Akiva S — Children's Hosp of Philadelphia
- Study coordinator: Cohen, Akiva S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.