Understanding how brain health changes with age and factors affecting it
THE ADMINISTRATION CORE (AC)
This study is looking for ways to understand how things like our genes, environment, and lifestyle affect brain health as we get older, especially for those at risk of Alzheimer's and similar conditions, and it involves checking in with 1,000 people over several years to see how their brains change over time.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-10909088 on NIH RePORTER |
What this research studies
This research focuses on identifying key factors that influence brain structure and function as people age, particularly in relation to Alzheimer's disease and related dementias. It involves collecting and analyzing data from 1,000 individuals over several years to understand how genetic, environmental, and lifestyle factors contribute to cognitive health. Participants will be involved in longitudinal assessments, which means their brain health will be monitored multiple times over an extended period. The study aims to create a comprehensive understanding of brain aging and resilience factors.
Who could benefit from this research
Good fit: Ideal candidates for participation are adults aged 21 and older, particularly those at risk for or experiencing cognitive dysfunction related to Alzheimer's disease.
Not a fit: Patients with acute cognitive impairments unrelated to aging or Alzheimer's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing or managing cognitive decline in aging populations.
How similar studies have performed: Previous research, such as the Human Connectome Project, has shown success in understanding brain connectivity and aging, suggesting that this approach has a solid foundation.
Where this research is happening
Saint Louis, United States
- Washington University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Ances, Beau M — Washington University
- Study coordinator: Ances, Beau M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.