Understanding how brain functions relate to mental health conditions

Examining the hierarchical structure of the RDoC framework using large-scale data-driven computational approaches

NIH-funded research Stanford University · NIH-11092945

This study is looking at how to better understand mental health conditions by connecting brain activity with behaviors, which could help improve how we diagnose and treat these issues for people like you.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionStanford University NIH-funded
Lab location1 site (Stanford, United States)
Project IDNIH-11092945 on NIH RePORTER

What this research studies

This research investigates the Research Domain Criteria (RDoC) framework, which aims to classify mental health disorders based on behavioral functions and their biological underpinnings. By utilizing large-scale data-driven computational approaches, the study seeks to validate and refine the RDoC framework to enhance its clinical application. Patients may benefit from this research as it explores the connections between brain activity and various psychological conditions, potentially leading to improved diagnostic and treatment methods. The research will involve analyzing data from diverse populations to ensure comprehensive insights into mental health.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals of all ages experiencing symptoms of mental health disorders, particularly those related to bipolar disorder.

Not a fit: Patients with mental health conditions that do not align with the constructs being examined in the RDoC framework may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate diagnoses and personalized treatment options for mental health disorders.

How similar studies have performed: Previous research has shown promise in using data-driven approaches to validate psychological frameworks, indicating potential for success in this novel application.

Where this research is happening

Stanford, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.