Understanding how brain function affects social thinking in early psychosis

Brain-Behavior Mechanisms of Social Cognition in First-Episode Psychosis

['FUNDING_OTHER'] · OHIO STATE UNIVERSITY · NIH-10890851

This study is looking at how the brain works when it comes to understanding other people's thoughts and feelings in people who are having their first episode of psychosis, and it hopes to find ways to help improve social skills and quality of life for them.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorOHIO STATE UNIVERSITY (nih funded)
Locations1 site (Columbus, UNITED STATES)
Trial IDNIH-10890851 on ClinicalTrials.gov

What this research studies

This research investigates the relationship between brain function and social cognition in individuals experiencing their first episode of psychosis. By using advanced imaging techniques like fMRI, the study aims to identify how brain areas involved in understanding others' thoughts and feelings are affected in these patients. It will also compare these findings with a control group to better understand the impact of social cognitive impairments on daily functioning. The goal is to provide insights that could lead to more effective interventions for improving social skills and overall quality of life.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals experiencing their first episode of psychosis who are seeking to understand and improve their social cognitive abilities.

Not a fit: Patients with chronic psychotic disorders or those who do not have significant social cognitive impairments may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatments that enhance social functioning and quality of life for individuals with first-episode psychosis.

How similar studies have performed: Previous research has shown that understanding brain-behavior relationships can lead to significant advancements in treating cognitive impairments in psychosis, suggesting this approach has potential for success.

Where this research is happening

Columbus, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.