Understanding how brain development and environment influence substance use in young people
Neurobehavioral pathways of polygenic and polyenvironmental effects on the onset and maintenance of substance involvement
This study is looking at how genes, environment, and behavior together influence substance use in teens and young adults, and it wants to find out when people are most at risk for using substances as their brains develop, so if you join, you'll help us learn more about these important connections!
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-10893978 on NIH RePORTER |
What this research studies
This research investigates the complex interactions between genetic, environmental, and neurobehavioral factors that contribute to substance use and disorders, particularly during adolescence and young adulthood. By examining how brain maturation affects emotional regulation and decision-making, the study aims to identify critical periods when individuals are most vulnerable to substance use. The research employs a combination of behavioral assessments and neuroimaging techniques to explore these relationships over a five-year period. Patients may be asked to participate in assessments that help researchers understand their experiences and behaviors related to substance use.
Who could benefit from this research
Good fit: Ideal candidates for participation include adolescents and young adults who are experiencing or at risk for substance use issues.
Not a fit: Patients who are not within the adolescent to young adult age range or those without any substance use concerns may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for substance use disorders in young people.
How similar studies have performed: Previous research has shown promising results in understanding the neurobehavioral mechanisms of substance use, suggesting that this approach could yield valuable insights.
Where this research is happening
Saint Louis, United States
- Washington University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Bogdan, Ryan H — Washington University
- Study coordinator: Bogdan, Ryan H
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.