Understanding how brain development affects risk behavior in adolescents with ADHD

Longitudinal Investigation of the Neurobiological Underpinnings of Risk Behavior in ADHD throughout the Adolescent Transition: The Key Role of Cognitive Control and Motivation Network Development

NIH-funded research Univ of North Carolina Chapel Hill · NIH-10841473

This study is looking at how the brains of teenagers with ADHD develop and how that affects their choices and behaviors, so we can find better ways to help them make safer decisions.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill NIH-funded
Lab location1 site (Chapel Hill, United States)
Project IDNIH-10841473 on NIH RePORTER

What this research studies

This research investigates the neurobiological factors that contribute to risk behaviors in adolescents diagnosed with ADHD. By examining brain development and cognitive control from late childhood to mid-adolescence, the study aims to identify how these factors influence decision-making and behavioral outcomes. Participants will undergo assessments that include brain imaging and behavioral evaluations to track changes over time. The goal is to better understand the connections between brain function and risk-taking behaviors, which can inform more effective interventions.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescents aged 12 to 20 who have been diagnosed with ADHD.

Not a fit: Patients outside the age range of 12 to 20 or those without a diagnosis of ADHD may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved identification and treatment strategies for adolescents with ADHD, potentially reducing their risk of negative outcomes.

How similar studies have performed: Previous research has shown promising results in understanding the neurobiological underpinnings of ADHD, suggesting that this approach could yield valuable insights.

Where this research is happening

Chapel Hill, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.