Understanding how brain damage affects speech in people with aphasia

Neural Bases of Vocal Sensorimotor Impairment in Aphasia

NIH-funded research University of Texas Dallas · NIH-11088694

This study is looking at how strokes on the left side of the brain affect speech and language in people with aphasia, and it aims to find ways to make speech therapy more effective by understanding how voice production and sensory feedback work together.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Texas Dallas NIH-funded
Lab location1 site (Richardson, United States)
Project IDNIH-11088694 on NIH RePORTER

What this research studies

This research investigates the impact of left hemisphere strokes on speech and language abilities in individuals with aphasia, a condition that severely impairs communication. The study aims to identify biomarkers that can help tailor treatments by focusing on both vocal motor production and sensory feedback mechanisms. By analyzing how these factors interact, the research seeks to improve the effectiveness of speech therapy for those affected by aphasia. Patients will be assessed to determine the integrity of their vocal sensorimotor functions, which could lead to more personalized and effective treatment strategies.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have experienced a left hemisphere stroke and are currently dealing with aphasia.

Not a fit: Patients who have not had a stroke or do not exhibit symptoms of aphasia may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved therapies that enhance communication abilities in individuals suffering from aphasia.

How similar studies have performed: Previous research has shown promise in using biomarkers to improve treatment outcomes for communication disorders, suggesting that this approach could be effective.

Where this research is happening

Richardson, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired brain injury
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.