Understanding how brain connectivity changes with age
CRCNS: Processing speed in the human connectome across the lifespan
This study is looking at how the connections in our brains change as we get older and how that affects how quickly and efficiently we think, using special electrodes placed in the brain for epilepsy treatment to gather important information.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-10636641 on NIH RePORTER |
What this research studies
This research investigates the changes in brain connectivity throughout a person's life, focusing on how these changes affect the speed and efficiency of information processing in the brain. By using electrical stimulation on intracranial electrodes, which are typically placed for epilepsy treatment, the study aims to analyze the functional communication across various brain pathways. The researchers will compile a large database of intracranial electroencephalography (iEEG) data to better understand these temporal properties of brain connectivity. This collaborative effort will help standardize the data structure for future studies.
Who could benefit from this research
Good fit: Ideal candidates for participation are individuals undergoing clinical treatment for epilepsy who have intracranial electrodes placed for monitoring.
Not a fit: Patients who do not have epilepsy or those who are not undergoing any form of brain surgery may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding of brain function and potentially enhance treatments for mental health disorders and cognitive decline.
How similar studies have performed: Previous research has shown promise in understanding brain connectivity through similar methodologies, indicating a potential for significant advancements in this area.
Where this research is happening
Rochester, United States
- Mayo Clinic Rochester — Rochester, United States (Active)
Researchers
- Principal investigator: Hermes, Dora — Mayo Clinic Rochester
- Study coordinator: Hermes, Dora
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.