Understanding how brain connectivity changes after a stroke

Shift from Unilateral to Bilateral Sensory-Motor Connectivity in Chronic Hemiparetic Stroke

['FUNDING_R01'] · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · NIH-10918117

This study is looking at how the brain changes after a stroke, especially for people who have trouble moving their arms and hands, to help find better ways to support recovery and improve movement.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN (nih funded)
Locations1 site (CHAMPAIGN, UNITED STATES)
Trial IDNIH-10918117 on ClinicalTrials.gov

What this research studies

This research investigates how the brain's sensory and motor pathways adapt following a stroke, particularly focusing on patients who experience abnormal movement patterns. It aims to understand the shift in sensory information processing from the affected side of the body to the unaffected side, which may contribute to difficulties in arm and hand function. By using advanced imaging techniques, the study will explore the relationship between these changes in brain connectivity and the motor impairments that arise after a stroke. The findings could provide insights into new rehabilitation strategies for stroke survivors.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have experienced a hemiparetic stroke and exhibit abnormal movement patterns in their affected limbs.

Not a fit: Patients who have not had a stroke or those with other neurological conditions unrelated to hemiparesis may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved rehabilitation techniques that enhance recovery of arm and hand function in stroke patients.

How similar studies have performed: Previous research has shown promising results in understanding brain connectivity changes after stroke, suggesting that this approach could yield valuable insights.

Where this research is happening

CHAMPAIGN, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acquired brain injury

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.