Understanding how brain connections form
Spatial and temporal regulation of synapse formation through phase separation
This work explores how brain cells make connections, called synapses, which is important for understanding conditions like autism.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Georgia Institute of Technology NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-11196061 on NIH RePORTER |
What this research studies
Our brains rely on tiny connections called synapses for communication between nerve cells, and how these connections form is a fundamental question in neuroscience. This project aims to uncover the molecular steps that guide the creation of these crucial connections. Researchers are focusing on how certain proteins come together to build these connections, using advanced techniques to observe this process. By understanding these basic building blocks, we hope to gain insights into how brain circuits develop and function.
Who could benefit from this research
Good fit: This foundational research does not involve direct patient participation but aims to benefit individuals with neurological conditions, such as autistic disorder, in the long term.
Not a fit: Patients seeking immediate treatment options or direct clinical intervention would not find direct benefit from this basic science project.
Why it matters
Potential benefit: If successful, this basic understanding could pave the way for new strategies to address neurological conditions, including autism, by targeting how brain connections are formed or repaired.
How similar studies have performed: Previous work by the researchers has shown that similar mechanisms are involved in forming these connections in simpler organisms, suggesting this approach is promising.
Where this research is happening
Atlanta, United States
- Georgia Institute of Technology — Atlanta, United States (Active)
Researchers
- Principal investigator: Mcdonald, Nathan — Georgia Institute of Technology
- Study coordinator: Mcdonald, Nathan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.