Understanding how brain connections change after traumatic brain injury
Detecting the disruption and recovery of synaptic connectivity after TBI
This study is looking at how a traumatic brain injury affects the connections between brain cells and how these changes might influence recovery and behavior, so we can better understand and improve treatments for patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Georgetown University NIH-funded |
| Lab location | 1 site (Washington, United States) |
| Project ID | NIH-10489713 on NIH RePORTER |
What this research studies
This research investigates the changes in synaptic connectivity that occur after a traumatic brain injury (TBI). By measuring synaptic integrity, the study aims to identify how these changes affect long-term behavioral outcomes in patients. The researchers will utilize non-invasive techniques to track synaptic health, which could help clinicians assess the effectiveness of various treatments over time. This approach may provide valuable insights into the recovery process following TBI.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who have experienced a traumatic brain injury.
Not a fit: Patients who have not experienced a traumatic brain injury or those with conditions unrelated to synaptic integrity may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved methods for monitoring recovery and tailoring treatments for individuals with traumatic brain injuries.
How similar studies have performed: Previous research has shown promise in using synaptic integrity measures to understand brain recovery, indicating that this approach has potential for success.
Where this research is happening
Washington, United States
- Georgetown University — Washington, United States (Active)
Researchers
- Principal investigator: Burns, Mark P — Georgetown University
- Study coordinator: Burns, Mark P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.