Understanding how brain circuits support memory and decision making
Development and organization of brain-wide neuronal ensemble circuits underlying memory and decision making
This study is looking at how certain brain areas work together to help us remember things and make decisions, using recordings from the brains of adult rats exploring new places, to better understand how our memories are formed and stored.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-11075312 on NIH RePORTER |
What this research studies
This research investigates the brain circuits involved in episodic memory and decision making, focusing on how neurons in the hippocampus and medial entorhinal cortex communicate during these processes. By using large-scale electrophysiological recordings from adult rodents navigating in new environments, the study aims to uncover the timing and coordination of neuronal activities that are crucial for memory encoding and consolidation. The findings could provide insights into how these cognitive functions develop and operate in the brain.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would be adults experiencing cognitive impairments or memory-related issues.
Not a fit: Patients with acute neurological conditions or those under 21 years old may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment of memory-related disorders.
How similar studies have performed: Previous research has successfully utilized similar approaches in studying memory and decision-making processes in animal models.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Dragoi, George — Yale University
- Study coordinator: Dragoi, George
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.