Understanding how brain circuits influence neural activity in mice
Investigating the microcircuit determinants of neural population activity through comparative analysis of latent dynamics across cortical areas in the mouse
This study looks at how the tiny connections in the brain work together to affect how groups of brain cells communicate, using mice to help us learn more about how different brain areas function and what makes them unique.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Georgia Institute of Technology NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-10937121 on NIH RePORTER |
What this research studies
This research investigates how the structure of brain microcircuits affects their function, particularly in relation to neural population activity. By analyzing the dynamics of neural activity across different cortical areas in mice, the study aims to uncover how variations in microcircuit composition can lead to specialized functions. The researchers utilize advanced techniques to record and analyze the activity of large populations of neurons, providing insights into the timescales of neural dynamics. This work could enhance our understanding of brain function and its underlying mechanisms.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research would include individuals with neurological conditions that affect brain function.
Not a fit: Patients with conditions unrelated to neural circuit function may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding of brain function, potentially informing treatments for neurological disorders.
How similar studies have performed: While this research explores novel approaches, similar studies have shown promise in understanding neural dynamics and microcircuit function.
Where this research is happening
Atlanta, United States
- Georgia Institute of Technology — Atlanta, United States (Active)
Researchers
- Principal investigator: Sederberg, Audrey — Georgia Institute of Technology
- Study coordinator: Sederberg, Audrey
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.