Understanding how brain circuits influence eating behavior and obesity

Top Down Regulation of Feeding-related Behavior

['FUNDING_R01'] · ALBERT EINSTEIN COLLEGE OF MEDICINE · NIH-11029446

This study looks at how certain brain cells help control our eating habits and decisions about food, which could help people understand how their brains influence hunger and weight management.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorALBERT EINSTEIN COLLEGE OF MEDICINE (nih funded)
Locations1 site (BRONX, UNITED STATES)
Trial IDNIH-11029446 on ClinicalTrials.gov

What this research studies

This research investigates the relationship between brain circuits and feeding behavior, particularly focusing on how specific neurons in the hypothalamus communicate with areas of the brain that control decision-making and habits. By examining the role of melanocortin peptides and their receptors, the study aims to uncover how these brain mechanisms affect cognitive functions related to food intake and obesity. Patients may benefit from insights into how their brain's processing of hunger and satiety cues can influence their eating habits and weight management.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults struggling with obesity or related eating disorders.

Not a fit: Patients who are not experiencing obesity or related cognitive issues may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for treating obesity by targeting brain circuits that regulate eating behavior.

How similar studies have performed: Previous research has shown promising results in understanding the brain's role in regulating eating behavior, suggesting that this approach could yield valuable insights.

Where this research is happening

BRONX, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: addictive disorder

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.