NIH-funded research R01 grant

Understanding how brain circuits influence eating behavior and obesity

Official title: Top Down Regulation of Feeding-related Behavior

Funded at Albert Einstein College of Medicine · NIH-11029446 · Data updated 2026-11-12

This study looks at how certain brain cells help control our eating habits and decisions about food, which could help people understand how their brains influence hunger and weight management.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionAlbert Einstein College of Medicine
NIH-funded
Lab location1 site (Bronx, United States)
Project startDecember 20, 2024
Project endNovember 20, 2029
Funding year2025
Award (this year)$499,761
NIH project number1R01DK141837-01
Project IDNIH-11029446 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adults struggling with obesity or related eating disorders.

Less likely to help

Patients who are not experiencing obesity or related cognitive issues may not benefit from this research.

What this research studies

This research investigates the relationship between brain circuits and feeding behavior, particularly focusing on how specific neurons in the hypothalamus communicate with areas of the brain that control decision-making and habits. By examining the role of melanocortin peptides and their receptors, the study aims to uncover how these brain mechanisms affect cognitive functions related to food intake and obesity. Patients may benefit from insights into how their brain's processing of hunger and satiety cues can influence their eating habits and weight management.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for treating obesity by targeting brain circuits that regulate eating behavior.

How similar studies have gone: Previous research has shown promising results in understanding the brain's role in regulating eating behavior, suggesting that this approach could yield valuable insights.

Where this research is happening

  • Albert Einstein College of Medicine
    Bronx, United States
    Active

Researchers

  • Principal investigator: Ross, Rachel a — Albert Einstein College of Medicine
  • Study coordinator: Ross, Rachel a

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.