Understanding how brain circuits influence decision-making and behavior

Models of computation in multi-regional circuits with thalamus in the middle

['FUNDING_OTHER'] · ALLEN INSTITUTE · NIH-11009599

This study is looking at how different parts of the brain work together to help us make decisions and remember things, especially when it comes to rewards, and it’s designed for anyone interested in understanding how our brains control these important activities.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorALLEN INSTITUTE (nih funded)
Locations1 site (SEATTLE, UNITED STATES)
Trial IDNIH-11009599 on ClinicalTrials.gov

What this research studies

This research investigates the complex interactions between different brain regions, particularly the cortex and thalamus, to understand how they influence decision-making and behaviors related to memory and rewards. By developing computational models, the project aims to uncover how these brain circuits generate and control various activity patterns that are essential for tasks requiring short-term memory and motor execution. The research will also explore how inputs from subcortical structures, such as the basal ganglia, contribute to these processes, potentially leading to insights into cognitive functions and disorders.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit from this research include individuals with cognitive disorders or those experiencing difficulties with decision-making and memory.

Not a fit: Patients with purely sensory processing issues or those without cognitive impairments may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and treatment of cognitive disorders and decision-making impairments.

How similar studies have performed: Other research has shown promise in understanding brain circuit dynamics, suggesting that this approach could yield valuable insights into cognitive functions.

Where this research is happening

SEATTLE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.