Understanding how brain circuits influence behavior and internal states
Identifying transcriptomic axes governing neural dynamics, behavior, and states
['FUNDING_CAREER'] · HARVARD UNIVERSITY · NIH-11033112
This study is looking at how different brain cells team up to help us respond to things around us, like when we eat, feel aggressive, or sleep, and it aims to find out how these processes change as we age or deal with different health issues, which could help improve our understanding of these behaviors.
Quick facts
| Phase | ['FUNDING_CAREER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | HARVARD UNIVERSITY (nih funded) |
| Locations | 1 site (CAMBRIDGE, UNITED STATES) |
| Trial ID | NIH-11033112 on ClinicalTrials.gov |
What this research studies
This research investigates how different types of brain cells work together to process environmental information and generate behaviors such as feeding, aggression, and sleep. By using advanced techniques like 2-photon microscopy, the study aims to monitor the activity of neurons in real-time while also analyzing their genetic profiles. This approach will help uncover the complex interactions between sensory inputs and internal states that drive behavior. Patients may benefit from insights gained about how these processes change with age or in response to various conditions.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would include individuals experiencing behavioral changes related to aging or neurological conditions.
Not a fit: Patients with stable behavioral patterns unrelated to age or neurological conditions may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for behavioral disorders and age-related changes in behavior.
How similar studies have performed: Other research has shown promise in using similar techniques to understand neural dynamics and behavior, indicating a potential for success in this area.
Where this research is happening
CAMBRIDGE, UNITED STATES
- HARVARD UNIVERSITY — CAMBRIDGE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SEO, CHANGWOO — HARVARD UNIVERSITY
- Study coordinator: SEO, CHANGWOO
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.