Understanding how brain circuits help recovery after a stroke

Cortical Circuits Underlying Functional Recovery Following Stroke

NIH-funded research Medical University of South Carolina · NIH-11083042

This study is looking at how certain brain cells help people recover after a stroke, using mice to learn more about the brain's wiring, so we can find better ways to help stroke survivors heal.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMedical University of South Carolina NIH-funded
Lab location1 site (Charleston, United States)
Project IDNIH-11083042 on NIH RePORTER

What this research studies

This research investigates the brain circuits involved in recovery following a stroke, which is a major cause of long-term disability. Using advanced two-photon imaging and optogenetic techniques in mice, the study aims to observe and manipulate specific neural circuits over time. By focusing on different types of neurons, the researchers hope to uncover how these cells contribute to recovery, ultimately leading to more effective treatments for stroke patients.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have experienced a stroke and are seeking ways to improve their recovery.

Not a fit: Patients who have not had a stroke or those with other unrelated neurological conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new therapies that enhance recovery for stroke patients.

How similar studies have performed: Previous research has shown promise in understanding brain recovery mechanisms, but this approach using specific neural circuit manipulation is relatively novel.

Where this research is happening

Charleston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.