Understanding how brain circuits help recovery after a stroke
Official title: Cortical Circuits Underlying Functional Recovery Following Stroke
Funded at Medical University of South Carolina · NIH-11083042 · Data updated 2026-11-12
This study is looking at how certain brain cells help people recover after a stroke, using mice to learn more about the brain's wiring, so we can find better ways to help stroke survivors heal.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Medical University of South Carolina NIH-funded |
| Lab location | 1 site (Charleston, United States) |
| Project start | May 1, 2023 |
| Project end | April 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $377,500 |
| NIH project number | 5R01NS131549-03 |
| Project ID | NIH-11083042 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have experienced a stroke and are seeking ways to improve their recovery.
✕Less likely to help
Patients who have not had a stroke or those with other unrelated neurological conditions may not benefit from this research.
What this research studies
This research investigates the brain circuits involved in recovery following a stroke, which is a major cause of long-term disability. Using advanced two-photon imaging and optogenetic techniques in mice, the study aims to observe and manipulate specific neural circuits over time. By focusing on different types of neurons, the researchers hope to uncover how these cells contribute to recovery, ultimately leading to more effective treatments for stroke patients.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that enhance recovery for stroke patients.
How similar studies have gone: Previous research has shown promise in understanding brain recovery mechanisms, but this approach using specific neural circuit manipulation is relatively novel.
Where this research is happening
-
Medical University of South Carolina
Charleston, United States Active
Researchers
- Principal investigator: Sato, Takashi — Medical University of South Carolina
- Study coordinator: Sato, Takashi
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.