Understanding how brain circuits control vocal communication in social contexts

Neural Circuits for Context-Dependent Control of Vocal Communication

NIH-funded research Cornell University · NIH-11061056

This study is looking at how the brain helps with talking and social interactions, especially for people with autism, by using mice to understand the brain pathways that control how we communicate in different social situations.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionCornell University NIH-funded
Lab location1 site (Ithaca, United States)
Project IDNIH-11061056 on NIH RePORTER

What this research studies

This research investigates the brain circuits involved in vocal communication, particularly in the context of autism spectrum disorder (ASD). By using advanced techniques in mice, the study aims to identify and characterize the neural pathways that regulate social vocalizations based on different social situations. The researchers will employ methods such as calcium imaging and neuronal silencing to explore how these circuits function and how they may differ during various social interactions. This work could provide insights into the underlying mechanisms of communication deficits seen in individuals with ASD.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with autism spectrum disorder who experience challenges with vocal communication.

Not a fit: Patients without autism spectrum disorder or those who do not exhibit vocal communication difficulties may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for improving vocal communication in individuals with autism spectrum disorder.

How similar studies have performed: Previous research has shown promise in understanding vocal communication through neural circuit analysis, suggesting that this approach could yield valuable insights.

Where this research is happening

Ithaca, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions autism spectral disorderautism spectrum disorderAutistic Disorderautistic spectrum disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.