Understanding how brain circuits control goal-directed behavior
Lateral habenula circuits for the regulation of goal-directed behavior
['FUNDING_R01'] · UNIVERSITY OF ARIZONA · NIH-11239290
This study is looking at how certain parts of the brain help us decide when to keep going after our goals or when to take a break, which could help us understand challenges faced by people with ADHD and addiction.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF ARIZONA (nih funded) |
| Locations | 1 site (TUCSON, UNITED STATES) |
| Trial ID | NIH-11239290 on ClinicalTrials.gov |
What this research studies
This research investigates the brain circuits involved in regulating whether we continue to pursue goals or decide to stop. It focuses on the lateral habenula (LHb), a brain region that plays a crucial role in balancing perseverance and disengagement based on our internal states and environmental cues. By studying how these circuits function, the research aims to uncover the mechanisms behind various psychiatric conditions, such as ADHD and addiction, which are linked to difficulties in managing goal-directed behavior. The approach includes animal models to explore how different factors influence decision-making related to goal pursuit.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing psychiatric conditions such as ADHD, addiction, or mood disorders.
Not a fit: Patients with conditions unrelated to goal-directed behavior regulation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for psychiatric disorders that affect goal-directed behavior.
How similar studies have performed: Previous research has shown promising results in understanding brain circuits related to behavior regulation, suggesting potential for breakthroughs in this area.
Where this research is happening
TUCSON, UNITED STATES
- UNIVERSITY OF ARIZONA — TUCSON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WARDEN, MELISSA RHOADS — UNIVERSITY OF ARIZONA
- Study coordinator: WARDEN, MELISSA RHOADS
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: addictive disorder, Attention deficit hyperactivity disorder