Understanding how brain circuits control eating behaviors
Mapping the neuronal circuitry underlying indirect striatal to hypothalamic connectivity and its role in feeding
['FUNDING_OTHER'] · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · NIH-10691531
This study is looking at how different parts of the brain work together to control eating habits, especially how the reward system influences how much we eat, and it could help us understand better ways to manage eating behaviors.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | RUTGERS BIOMEDICAL AND HEALTH SCIENCES (nih funded) |
| Locations | 1 site (Newark, UNITED STATES) |
| Trial ID | NIH-10691531 on ClinicalTrials.gov |
What this research studies
This research investigates the complex neuronal circuitry that regulates feeding behaviors, focusing on how different brain regions interact to control caloric intake. The study aims to map the connections between the striatum, which is involved in reward processing, and the lateral hypothalamus, a key area for feeding regulation. By employing advanced techniques like viral tracing and chemogenetics, researchers will explore the specific cell types involved in these pathways. This work could provide insights into the mechanisms of eating behaviors and potential targets for interventions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing issues related to eating behaviors, such as obesity or eating disorders.
Not a fit: Patients who do not have any concerns related to feeding behaviors or metabolic disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for managing eating disorders and obesity by targeting specific brain circuits.
How similar studies have performed: Previous research has shown promising results in understanding the brain's role in feeding behaviors, indicating that this approach could yield valuable insights.
Where this research is happening
Newark, UNITED STATES
- RUTGERS BIOMEDICAL AND HEALTH SCIENCES — Newark, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BOCARSLY, MIRIAM E. — RUTGERS BIOMEDICAL AND HEALTH SCIENCES
- Study coordinator: BOCARSLY, MIRIAM E.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.