Understanding how brain circuits communicate in chronic pain
Corticothalamic network function in chronic pain
This study is looking at how different parts of the brain work together to create the feeling of chronic pain, and it's for anyone who wants to understand how things like mood and expectations can affect their pain experience.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-11113880 on NIH RePORTER |
What this research studies
This research investigates the complex nature of chronic pain by examining how different brain circuits communicate with each other. It aims to uncover the mechanisms through which sensory, cognitive, and emotional information is integrated to create the experience of pain. By using direct recordings from the brain and advanced analytical methods, the study will explore how specific brain regions interact and how these interactions may change over time. The research will also look at how factors like mood and expectations can influence pain perception in both controlled and real-world settings.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from chronic pain conditions who are willing to participate in brain recording procedures.
Not a fit: Patients with acute pain or those who do not have chronic pain conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for managing and treating chronic pain more effectively.
How similar studies have performed: Previous research has shown promise in understanding brain networks related to pain, but this study aims to provide deeper insights using novel methodologies.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Shirvalkar, Prasad — University of California, San Francisco
- Study coordinator: Shirvalkar, Prasad
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.