Understanding how brain circuits affect maternal behavior

The Role of Corticolimbic Circuits in Maternal Behavior

['FUNDING_R01'] · RUTGERS, THE STATE UNIV OF N.J. · NIH-10779818

This study looks at how becoming a mother changes the way the brain works, especially in how it helps with caring for babies and handling stress, and it aims to find ways to support moms in feeling better so they can take care of their little ones more easily.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorRUTGERS, THE STATE UNIV OF N.J. (nih funded)
Locations1 site (PISCATAWAY, UNITED STATES)
Trial IDNIH-10779818 on ClinicalTrials.gov

What this research studies

This research investigates the changes in brain function and physiology that occur during the transition to motherhood, focusing on the neural circuits that regulate maternal care and responses to stress. By studying both human and animal models, the research aims to uncover how these brain circuits interact and influence maternal behaviors. The project employs advanced techniques such as genetic technologies, neural-circuit dissection, and synaptic electrophysiology to explore the mechanisms behind maternal care and emotional responses. The goal is to better understand how improving a mother's emotional state can enhance her ability to care for her offspring.

Who could benefit from this research

Good fit: Ideal candidates for this research include new mothers or those experiencing challenges related to maternal care and emotional well-being.

Not a fit: Patients who are not mothers or who do not have any maternal responsibilities may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved interventions for mothers experiencing stress, ultimately benefiting both maternal and child health.

How similar studies have performed: Previous research has shown promising results in understanding the role of brain circuits in maternal behavior, suggesting that this approach could yield valuable insights.

Where this research is happening

PISCATAWAY, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.