Understanding how brain circuits affect long-term social memory.
Investigating the role of hippocampocortical circuitry in long term social memory.
['FUNDING_FELLOWSHIP'] · UNIVERSITY OF COLORADO · NIH-10995289
This study is looking at how the brain helps us remember social interactions, which can be a challenge for people with Alzheimer's, and it uses mice to learn more about the brain areas involved, hoping to find new ways to help improve social memory for those affected.
Quick facts
| Phase | ['FUNDING_FELLOWSHIP'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF COLORADO (nih funded) |
| Locations | 1 site (Boulder, UNITED STATES) |
| Trial ID | NIH-10995289 on ClinicalTrials.gov |
What this research studies
This research investigates the neural mechanisms that support long-term social memory, which is often impaired in conditions like Alzheimer's disease. By studying the communication between specific brain regions, particularly the ventral hippocampus and medial prefrontal cortex, the project aims to uncover how social memories are formed and retained. The research utilizes mouse models to explore these brain circuits and their role in social recognition and memory consolidation. Insights gained could lead to new therapeutic approaches for improving social memory in affected individuals.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Alzheimer's disease or related neuropsychiatric disorders that affect social memory.
Not a fit: Patients without cognitive impairments or those not experiencing social memory deficits may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that enhance social memory in patients with neuropsychiatric disorders.
How similar studies have performed: Previous research has shown promising results in understanding memory mechanisms in animal models, suggesting potential for breakthroughs in this area.
Where this research is happening
Boulder, UNITED STATES
- UNIVERSITY OF COLORADO — Boulder, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SHEERAN, WILLIAM M — UNIVERSITY OF COLORADO
- Study coordinator: SHEERAN, WILLIAM M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease