Understanding how brain circuits affect binge-eating disorder symptoms
The Computational Role of Corticostriatal Circuits in Binge-Eating Disorder Symptoms and Severity
This study is looking at how the brain works in people with binge-eating disorder to better understand why they make certain eating choices, with the hope of finding new ways to help them.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10747430 on NIH RePORTER |
What this research studies
This research investigates the brain mechanisms that contribute to binge-eating disorder (BED), a condition affecting many individuals in the U.S. The study aims to identify how changes in brain circuits influence decision-making related to eating behaviors. By combining computational modeling with advanced brain imaging techniques, researchers will explore the relationship between neural connectivity and the severity of binge-eating symptoms. This approach seeks to uncover new targets for treatment by understanding the underlying neurobiological factors of BED.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who experience symptoms of binge-eating disorder.
Not a fit: Patients who do not have binge-eating disorder or related eating disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for individuals suffering from binge-eating disorder.
How similar studies have performed: Previous research has shown promise in understanding brain mechanisms related to eating disorders, but this specific neurocomputational approach is relatively novel.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Berner, Laura a. — Icahn School of Medicine at Mount Sinai
- Study coordinator: Berner, Laura a.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.