Understanding how brain changes affect thinking in Alzheimer's disease and aging.
Statistical method for neural mechanism mediating and moderating cognitive system in Alzheimer's disease and aging research.
['FUNDING_R01'] · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · NIH-10767238
This study is looking at how things like education and life experiences affect thinking skills in people with Alzheimer's and those who are aging normally, and it’s for anyone interested in understanding how our brains stay healthy as we get older.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-10767238 on ClinicalTrials.gov |
What this research studies
This research investigates how cognitive changes in Alzheimer's disease and normal aging are influenced by various factors such as education and life experiences. It aims to develop new statistical tools to analyze brain imaging and cognitive data from individuals with different cognitive states, including normal aging and Alzheimer's disease. By utilizing advanced neuroimaging techniques, the study seeks to uncover the neural mechanisms that contribute to cognitive resilience. Participants' data will be drawn from established studies to ensure a comprehensive analysis of the effects of cognitive reserve on brain health.
Who could benefit from this research
Good fit: Ideal candidates for this research include older adults, particularly those experiencing cognitive changes or at risk for Alzheimer's disease.
Not a fit: Patients with early-stage Alzheimer's disease who do not have measurable cognitive changes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and potentially new strategies for preserving cognitive function in aging and Alzheimer's disease.
How similar studies have performed: Previous research has shown promise in using neuroimaging and cognitive assessments to understand brain function in aging, indicating that this approach may yield valuable insights.
Where this research is happening
NEW YORK, UNITED STATES
- NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LEE, SEONJOO — NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC
- Study coordinator: LEE, SEONJOO
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.